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Publications 2021

Doray A., Lemoine R., Severin M., Chadet S., Lopez-Charcas O., Héraud A., Baron C., Besson P., Monteil A., F. Pedersen S., Roger S.. The voltage-gated sodium channel beta4 subunit maintains epithelial phenotype in mammary cells. Cells, 29 juin 2021.
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Angoulvant D, Ducluzeau PH, Renoult-Pierre P, Fauchier G, Herbert J, Semaan C, Bodin A, Bisson A, Fauchier L. Impact of gender on relative rates of cardiovascular events in patients with diabetes. Diabetes Metab. 2021 Jan 14:101226. doi: 10.1016/j.diabet.2021.101226. Online ahead of print. PMID: 33454437

Piollet M, Sturza A, Chadet S, Gabillard-Lefort C, Benoist L, Muntean DM, Aburel OM, Angoulvant D, Ivanes F. P2Y11 Agonism Prevents Hypoxia/Reoxygenation- and Angiotensin II-Induced Vascular Dysfunction and Intimal Hyperplasia Development. Int J Mol Sci. 2021 Jan 16;22(2):E855. doi: 10.3390/ijms22020855.PMID: 33467058

Le Tilly O, Azzopardi N, Bonneau C, Desvignes C, Oberkampf F, Ezzalfani M, Ternant D, Turbiez I, Gutierrez M, Paintaud G. Antigen mass may influence trastuzumab concentrations in cerebrospinal fluid after intrathecal administration. Clin Pharmacol Ther. 2021 Feb 5. doi: 10.1002/cpt.2188. Online ahead of print.

Fauchier L, Fauchier G, Angoulvant D. Empagliflozin in Heart Failure. N Engl J Med. 2021 Jan 28;384(4):385. doi: 10.1056/NEJMc2033669

Troubat R, Leman S, Pinchaud K, Surget A, Barone P, Roger S, Marie Le Guisquet A, Brizard B, Belzung C, Camus V. Brain immune cells characterization in UCMS exposed P2X7 Knock-Out mouse. Brain Behav Immun. 2021 Feb 17:S0889-1591(21)00054-4. doi: 10.1016/j.bbi.2021.02.012.

Mayor A, Chesnay A, Desoubeaux G, Ternant D, Heuzé-Vourc'h N, Sécher T. Therapeutic Antibodies for the Treatment of Respiratory Tract Infections-Current Overview and Perspectives. Vaccines (Basel). 2021 Feb 13;9(2).

Desvignes, C., Ternant, D., Lecomte, T., Lièvre, A., Ohresser, M., Chautard, R., Raoul, W., Paintaud, G. A robust enzyme-linked immunosorbent assay to measure serum ramucirumab concentrations. Bioanalysis. 2021 Mar 26. doi: 10.4155/bio-2020-0199

de Freminville, JB ; Vernier, LM ; Roumy, J ; Patat, F ; Gatault, P ; Sautenet, B & al. Early changes in renal resistive index and mortality in diabetic and nondiabetic kidney transplant recipients: a cohort study. BMC Nephrol. 2021 Feb 19;22(1):62. doi: 10.1186/s12882-021-02263-8.

Chautard R, Corset L, Ibrahim S, Desvignes C, Paintaud G, Baroukh N, Guéguinou M, Lecomte T, Raoul W. Anti-EGFR monoclonal antibodies panitumumab and cetuximab affect differently miRNA expression in colorectal cancer cells. Biomark Med,

Lopez-Charcas O., Pukkanasut P., E. Velu S., J. Brackenbury W., G. Hales T., Besson P, Carlos Gomora J., Roger S. Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers. iScience. Volume 24, issue 4, 102270, april 23, 2021. https://www.cell.com/iscience/pdf/S2589-0042(21)00238-8.pdf

Granel J, Korkmaz B, Nouar D, Weiss SAI, Jenne DE, Lemoine R, Hoarau C. Pathogenicity of Proteinase 3-Anti-Neutrophil Cytoplasmic Antibody in Granulomatosis With Polyangiitis: Implications as Biomarker and Future Therapies. Front Immunol. 2021 Feb 18;12:571933. doi: 10.3389/fimmu.2021.571933. eCollection 2021.PMID: 33679731 Free PMC article. Review.

Ngo Ntjam N., Thulliez M., Paintaud G., Salvo F., Angoulvant D., Pisella J-P., Bejan-Angoulvant T.. Cardiovascular adverse events with intravitreal anti–vascular endothelial growth factor drugs. A systematic review and meta-analysis of randomized clinical trials. JAMA Ophthalmology. Published online April 15, 2021. doi:10.1001/jamaophthalmol.2021.0640

Clementy, N.; Bodin, A.; Bisson, A.; Teixeira-Gomes, A.-P.; Roger, S.; Angoulvant, D.; Labas, V.; Babuty, D. The Defibrillation Conundrum: New Insights into the Mechanisms of Shock-Related Myocardial Injury Sustained from a Life-Saving Therapy. Int. J. Mol. Sci. 2021, 22, 5003. https://doi.org/ 10.3390/ijms22095003

Jiang, Lin-Hua, Emily A. Caseley, Steve P. Muench, et Roger S.. Structural Basis for the Functional Properties of the P2X7 Receptor for Extracellular ATP. Purinergic Signalling, 13 mai 2021. https://doi.org/10.1007/s11302-021-09790-x.

Thibault G., Paintaud G., Cheng Sung H., Lajoie L., Louis E., the GETAID, Desvignes C., Watier H., Gouilleux-Gruart V., Ternant D.. Association of IgG1 Antibody Clearance with FcγRIIA Polymorphism and Platelet Count in Infliximab-Treated Patients. International Journal of molecular sciences, 3 juin 2021.

Petitcollin A., Azzopardi N., Pierga J.Y., Ternant D., Desvignes C., Navarro-Teulon I., Mouret-Reynier MA., Coudert B., Paintaud G.. Population pharmacokinetics and exposure-response relationship of trastuzumab and bevacizumab in early breast cancer. Eur J Clin Pharmacol. Juin 2021.

Jiang LH, Adinolfi E, Roger S. Editorial: Ion Channel Signalling in Cancer: From Molecular Mechanisms to Therapeutics. Front Pharmacol. 2021 Jun 3;12:711593. doi: 10.3389/fphar.2021.711593. eCollection 2021

Petitcollin A, Azzopardi N, Pierga JY, Ternant D, Navarro-Teulon I, Desvignes C, Mouret-Reynier MA, Coudert B, Paintaud G. Population pharmacokinetics and exposure-response relationship of trastuzumab and bevacizumab in early-stage breast cancer. Eur J Clin Pharmacol. 2021 Jul 10. doi: 10.1007/s00228-021-03179-w. Online ahead of print. PMID: 34245336

Azzopardi N, Longuet H, Ternant D, Thibault G, Gouilleux-Gruart V, Lebranchu Y, Büchler M, Gatault P, Paintaud G. Relationship Between Antithymocyte Globulin Concentrations and Lymphocyte Sub-Populations in Kidney Transplant Patients. Clin Pharmacokinet. 2021 Jul 22. doi: 10.1007/s40262-021-01053-7. Online ahead of print.

Ternant D., Pfister M., Le Tilly O., Mulleman D., Picon L., Willot S., Passot C., Bejan‑Angoulvant T,. Lecomte T., Paintaud G., Koch G.. Infiximab Treatment Does Not Lead to Full TNF‑α Inhibition: A Target‑Mediated Drug Disposition Model. Clinical Pharmacokinet. Accepted: 6 July 2021

Marin C, Khoudour N, Millet A, Lebert D, Bros P, Thomas F, Ternant D, Lacarelle B, Guitton J, Ciccolini J, Blanchet B. Cross-Validation of a Multiplex LC-MS/MS Method for Assaying mAbs Plasma Levels in Patients with Cancer: A GPCO-UNICANCER Study. Pharmaceuticals (Basel). 2021 Aug 12;14(8) .

Ait-Oufella H, Yu M, Kotti S, Georges A, Vandestienne M, Joffre J, Roubille F, Angoulvant D, Santos-Zas I, Tedgui A, Gibot S, Derive M, Danchin N, Bouatia-Naji N, Simon T. Plasma and genetic determinants of soluble TREM-1 and major adverse cardiovascular events in a prospective cohort of acute myocardial infarction patients. Results from the FAST-MI 2010 study. Int J Cardiol. 2021 Sep 15:S0167-5273(21)01379-6. doi: 10.1016/j.ijcard.2021.09.018. Online ahead of print. PMID: 34534607

Bennani Rtel, M., Ternant, D., Büchler, M., El Hassouni, M., Khabbal, Y., Achour, S., Sqalli, T.. 2021. Food and lipid intake alters the pharmacokinetics of cyclosporine in kidney transplants. Fundam Clin Pharmacol 35: 446-454. https://doi.org/10.1111/fcp.12591

Bailly M, Thibault F, Courtehoux M, Metrard G, Angoulvant D, Ribeiro MJ. Myocardial Flow Reserve Measurement During CZT-SPECT Perfusion Imaging for Coronary Artery Disease Screening: Correlation With Clinical Findings and Invasive Coronary Angiography-The CFR-OR Study. Front Med (Lausanne). 2021 Jun 4;8:691893. doi: 10.3389

Bensalem, A., Cartron, G., Specks, U., Mulleman, D., Gyan, E., Cornec, D., Desvignes, C., Casasnovas, O., Lamy, T., Leprêtre, S., Paintaud, G., Ternant, D. 2021. The influence of underlying disease on rituximab pharmacokinetics may be explained by target-mediated drug disposition. Clin Pharmacokinet. accepted Nov 13. htpps://doi.org/10.1007/s40262-021-01081-3

Buisson A, Filippi J, Amiot A, Cadiot G, Allez M, Marteau P, Bouhnik Y, Pineton de Chambrun G, Pelletier AL, Nancey S, Moussata D, Attar A, Blain A, Vuitton L, Vernier-Massouille G, Seksik P, Nachury M, Dupas JL, Laharie D, Peyrin-Biroulet L, Louis E, Mary JY.Defining and Assessing the Reproducibility of Crohn's Disease Endoscopic Lesions: A Delphi-like Method from the GETAID. J Crohns Colitis. 2021 Jun 22;15(6):1000-1008. doi: 10.1093/ecco-jcc/jjaa250

Bodin A, Bisson A, Andre C, Babuty D, Clementy N. Anodal Capture for Multisite Pacing with a Quadripolar Left Ventricular Lead: A Feasibility Study. J Clin Med. 2021 Dec 15;10(24):5886. doi: 10.3390/jcm10245886.

Bordy R., Moretto J., Devaux S., Wendling D., Moretto-Riedweg K., Demougeot C., Totoson P.. Adjuvant-induced arthritis is a relevant model to mimic coronary and myocardial impairments in rheumatoid arthritis Joint Bone Spine. 2021;88(1):105069. doi: 10.1016/j.jbspin.2020.09.001

Campone C, Bachelot T, Treilleux I, Pistilli B, Salleron J, Seegers V, Arnedos M, Loussouarn D, Wang Q, Vanlemmens L, Jimenez M, Rios M, Diéras V, Leroux A, Paintaud G, Rezai K, André F, Lion M, Merlin JL. A phase II randomized study of preoperative trastuzumab alone or combined to everolimus in early HER2-positive breast cancer patients and predictive biomarkers (RADHER trial). Eur J Cancer 2021, 158: 169-180. https://doi.org/10.1016/j.ejca.2021.09.017

Chemouny JM, Bobot M, Sannier A, Maisons V, Jourde-Chiche N, Ferriere E, Joly D, Vigneau C, Rioux-Leclercq N, Barba C, Daniel L, Halimi JM, Vrtovsnik F. Kidney Biopsy in Type 2 Diabetes: A Multicenter Cross-Sectional Study. Am J Nephrol. 2021;52(2):131-140. doi: 10.1159/000514259. Epub 2021 Mar 29. PMID:33780924.

Clementy N, Bisson A, Bodin A, Herbert J, Lacour T, Etienne CS, Pierre B, Deharo P, Babuty D, Fauchier L. Outcomes associated with pacemaker implantation following transcatheter aortic valve replacement: A nationwide cohort study. Heart Rhythm. 2021 Dec;18(12):2027-2032. doi: 10.1016/j.hrthm.2021.06.1175.

Clementy N, Coelho R, Veltmann C, Marijon E, Tolosana J, Galand V, Ploux S, Eschalier R, Simeon E, Blessberger H, Mueller-Leisse J, Pujol-Lopez M, Martins R, Ritter P, Steinwender C, Babuty D. Leadless pacemakers in critically ill patients requiring prolonged cardiac pacing: A multicenter international study. J Cardiovasc Electrophysiol. 2021 Sep;32(9):2522-2527. doi: 10.1111/jce.15175. Epub 2021 Jul 22.

Deharo P, Cuisset T, Bisson A, Herbert J, Lacour T, Etienne CS, Jaussaud N, Morera P, Spychaj JC, Porto A, Collart F, Theron A, Bernard A, Bourguignon T, Fauchier L. Outcomes Following Aortic Stenosis Treatment (Transcatheter vs Surgical Replacement) in Women vs Men (From a Nationwide Analysis). Am J Cardiol. 2021 Sep 1;154:67-77. doi: 10.1016/j.amjcard.2021.05.046. Epub 2021 Jul 10. PMID: 34256941

Denormandie P, Simon T, Cayla G, Steg PG, Montalescot G, Durand-Zaleski I, Le Bras A, Le Breton H, Valy Y, Schiele F, Cuisset T, Vanzetto G, Levesque S, Goube P, Nallet O, Angoulvant D, Roubille F, Charles-Nelson A, Chatellier G, Danchin N, Puymirat E. Compared Outcomes of ST-Elevation Myocardial Infarction Patients with Multivessel Disease Treated with Primary Percutaneous Coronary Intervention and Preserved Fractional Flow Reserve of Non-Culprit Lesions Treated Conservatively and of Those with Low Fractional Flow Reserve Managed Invasively: Insights from the FLOWER MI trial. Circ Cardiovasc Interv. 2021 Aug 23. doi: 10.1161/CIRCINTERVENTIONS.121.011314. Online ahead of print. PMID: 34420366.

Desgrouas M, Merdji H, Bretagnol A, Barin-Le Guellec C, Halimi JM, Ehrmann S, Salmon Gandonnière C. Kinetic Glomerular Filtration Rate Equations in Patients With Shock: Comparison With the Iohexol-Based Gold-Standard Method. Crit Care Med. 2021 Aug 1;49(8):e761-e770. doi: 10.1097/CCM.0000000000004946. PMID: 33710029.

EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Lancet. 2021 Sep 7:S0140-6736(21)01122-3. doi: 10.1016/S0140-6736(21)01122-3. Online ahead of print. PMID: 34506743

Fauchier G, Bisson A, Bodin A, Herbert J, Semaan C, Angoulvant D, Ducluzeau PH, Lip GYH, Fauchier L. Metabolically healthy obesity and cardiovascular events: A nationwide cohort study. Diabetes Obes Metab. 2021 Jul 12. doi: 10.1111/dom.14492. Online ahead of print.PMID: 34251088

Fauchier G, Bisson A, Bodin A, Herbert J, Angoulvant D, Ducluzeau PH, Lip GYH, Fauchier L. Glucose-lowering drug use and new-onset atrial fibrillation in patients with diabetes mellitus. Diabetologia. 2021 Aug 25. doi: 10.1007/s00125-021-05551-y. Online ahead of print.

Fauchier L, Bisson A, Bodin A, Herbert J, Spiesser P, Pierre B, Clementy N, Bernard A, Babuty D, Lip GYH. Ischemic Stroke in Patients With Hypertrophic Cardiomyopathy According to Presence or Absence of Atrial Fibrillation. Stroke. 2021 Oct 4:STROKEAHA121034213. doi: 10.1161/STROKEAHA.121.034213. Online ahead of print.

Gagez, A.-L., Paul, F., Alaterre, E., Gouilleux-Gruart, V., Tuaillon, E., Lepretre, S., Ternant, D., Letestu, R., Moreaux, J., Cartron, G.. 2021. Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study. Leuk Lymphoma. 62(13):3160-3169. htpps://doi.org/10.1080/10428194.2021.1955879

Gallo A, Pérez de Isla L, Charrière S, Vimont A, Alonso R, Muñiz-Grijalvo O, Díaz-Díaz JL, Zambón D, Moulin P, Bruckert E, Mata P, Béliard S; REFERCHOL and SAFEHEART investigators. The Added Value of Coronary Calcium Score in Predicting Cardiovascular Events in Familial Hypercholesterolemia. JACC Cardiovasc Imaging. 2021 Jul 8:S1936-878X(21)00501-5. doi: 10.1016/j.jcmg.2021.06.011. Online ahead of print. PMID: 34274263

Guéguinou, M., Felix, R., Marionneau-Lambot, S., Oullier, T., Penna, A., Kouba, S., Gambade, A., Fourbon, Y., Ternant, D., Arnoult, C., Simon, G., Bouchet, A.-M., Chantôme, A., Harnois, T., Haelters, J.-P., Jaffrès, P.-A., Weber, G., Bougnoux, P., Carreaux, F., Mignen, O., Vandier, C., Potier-Cartereau, M.. 2021. Cell Calcium 97:102435. https://doi.org/0.1016/j.ceca.2021.102435

Halimi JM. Complications after native kidney biopsy: definitive data. Curr Opin Nephrol Hypertens. 2021 Aug 18. doi: 10.1097/MNH.0000000000000736. Epub ahead of print. PMID: 34412087.

Halimi JM, Gatault P, Longuet H, Barbet C, Goumard A, Gueguen J, Goin N, Sautenet B, Herbert J, Bisson A, Fauchier L. Major Bleeding of Transjugular Native Kidney Biopsies. A French Nationwide Cohort Study. Kidney Int Rep. 2021 Jul 17;6(10):2594-2603. doi: 10.1016/j.ekir.2021.07.011. PMID: 34622099; PMCID:PMC8484497.

Halimi JM, Ortiz A, Sarafidis PA, Mallamaci F, Wuerzner G, Pisano A, London., G, Persu A, Rossignol P, Sautenet B, Ferro C, Boletis J, Kanaan N, Vogt L, Bolignano D, Burnier M, Zoccali C. Hypertension in kidney transplantation: a consensus statement of the 'hypertension and the kidney' working group of the European Society of Hypertension. J Hypertens. 2021 Aug 1;39(8):1513-1521. doi:10.1097/HJH.0000000000002879.

Jacobs M, Bisson A, Bodin A, Babuty D, Niro M, Clementy N. Leadless cardiac pacemaker implantation in patient with active tricuspid endocarditis. Europace. 2021 Nov 8;23(11):1794. doi: 10.1093/europace/euab081.

Kokkali, S., Ternant, D., Kemmel, V., Levêque, D., Wendling, F., Barthelemy. P., Kurtz, J.-E.. 2021. Intravenous and subcutaneous administration of trastuzumab in a patient on peritoneal dialysis. Brit J Clin Pharmacol 87: 3372-3374. https://doi.org/ 10.1111/bcp.14731

Lantelme P, Bisson A, Lacour T, Herbert J, Ivanes F, Bourguignon T, Angoulvant D, Harbaoui B, Bonnet M, Babuty D, Saint Etienne C, Deharo P, Fauchier L. Timing of Coronary Revascularization and Transcatheter Aortic Valve Replacement: An Observational Nationwide Cohort Analysis. JACC Cardiovasc Interv. 2021 Feb 22;14(4):484-486. doi: 10.1016/j.jcin.2020.11.040.

Lenga Ma Bonda W., Lavergne M., Vasseur V., Brisson L., Roger S., Legras A., Guillon A., Guyétant S., Hiemstra P.S., Si-Tahar M., Iochmann S., Reverdiau P. Kallikrein-related peptidase 5 contributes to the remodeling and repair of bronchial epithelium. FASEB J. 2021 Oct;35(10):e21838. doi: 10.1096/fj.202002649R.

Le Tilly O, Bejan-Angoulvant T, Paintaud G, Ternant D.. Letter to Dreesen et al. on their article "Modelling of the Relationship Between Infliximab Exposure, Faecal Calprotectin, and Endoscopic Remission in Patients With Crohn's Disease"-A comprehensive review of infliximab population pharmacokinetic modelling publications. Br J Clin Pharmacol. 2021 Mar;87(3):1594-1595. doi: 10.1111/bcp.14554.

Le Tilly, O., Paintaud, G., Ternant, D., 2021. Therapeutic Drug Monitoring of Infliximab in Patients With Chronic Immune-Mediated Inflammatory Diseases (letter). JAMA 326(11):1069. https://pubmed.ncbi.nlm.nih.gov/34546307

Ma I, Genet T, Clementy N, Bisson A, Herbert J, Semaan C, Bouteau J, Angoulvant D, Ivanes F, Fauchier L. Outcomes in patients with acute myocardial infarction and history of illicit drug use: a French nationwide analysis. Eur Heart J Acute Cardiovasc Care. 2021 Aug 28:zuab073. doi: 10.1093/ehjacc/zuab073. Online ahead of print.PMID: 34453835

Maïer B, Gory B, Lapergue B, Sibon I, Escalard S, Kyheng M, Labreuche J, de Havenon A, Petersen N, Anadani M, Gayat E, Boursin P, Ben Maacha M, Desilles JP, Blanc R, Piotin M, Halimi JM, Mazighi M; BP-TARGET investigators. Effect of blood pressure variability in the randomized controlled BP TARGET trial. Eur J Neurol. 2021 Nov 25. doi: 10.1111/ene.15194. Epub ahead of print. PMID: 34821437.

Marin, C., Khoudour, N., Millet, A., Lebert, D., Bros, P., Thomas, F., Ternant, D., Lacarelle, B., Guitton, J., Ciccolini, J., Blanchet, B.. 2021. Cross-Validation of a multiplex LC-MS/MS method for assaying mAbs plasma levels in patients with cancer: A GPCO-UNICANCER study. Pharmaceuticals (Basel). Aug 12;14(8). https://doi.org/10.3390/ph14080796

Mewton N, Roubille F, Bresson D, Prieur C, Bouleti C, Bochaton T, Ivanes F, Dubreuil O, Biere L, Hayek A, Derimay F, Akodad M, Alos B, Haider L, El Jonhy N, Daw R, De Bourguignon C, Dhelens C, Finet G, Bonnefoy-Cudraz E, Bidaux G, Boutitie F, Maucort-Boulch D, Croisille P, Rioufol G, Prunier F, Angoulvant D. Effect of Colchicine on Myocardial Injury in Acute Myocardial Infarction. Circulation. 2021 Sep 14;144(11):859-869. doi: 10.1161/CIRCULATIONAHA.121.056177. Epub 2021 Aug 23. PMID: 34420373.

Moret L, Ganea A, Dao M, Hummel A, Knebelman B, Subra JF, Noble J, Mariat C, Jourde-Chiche N, Toure F, Garrouste C, Laurent C, Adeline L, Delmas Y, Cez A, Fritz O, Mousson C, Pouteau LM, Moranne O, Halimi JM, Audard V. Apheresis in Adult With Refractory Idiopathic Nephrotic Syndrome on Native Kidneys. Kidney Int Rep. 2021;6(8):2134-2143.

Ortiz A, Ferro CJ, Balafa O, Burnier M, Ekart R, Halimi JM, Kreutz R, Mark PB, Persu A, Rossignol P, Ruilope LM, Schmieder RE, Valdivielso JM, Del Vecchio L, Zoccali C, Mallamaci F, Sarafidis P; European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association—European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and Kidney working group of the European Society of Hypertension (ESH). Mineralocorticoid receptor antagonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease. Nephrol Dial Transplant. 2021 May 4:gfab167. doi: 10.1093/ndt/gfab167.

Passot, C., Sberro-Soussan, R., Bertrand, D., Caillard, S., Schvartz, B., Domenger, C., Contin-Bordes, C., Paintaud, G., Halimi JM, Ternant D, Gatault P. 2021. Feasibility and safety of tailored dosing schedule for eculizumab based on therapeutic drug monitoring: Lessons from a prospective multicentric study. Br J Clin Pharmacol. May;87(5):2236-2246. https://doi.org/10.1111/bcp.14627.

Passot, C., Sberro-Soussan, R., Bertrand, D., Caillard, S., Schvartz, B., Domenger, C., Bordes, C., Paintaud, G., Halimi, J.-M., Ternant, D., Gatault, P.. 2021. Feasibility and safety of tailored dosing schedule for eculizumab based on therapeutic drug monitoring: lessons from a prospective multicentric study. Br J Clin Pharmacol 87 (5) : 2236-2246. https://pubmed.ncbi.nlm.nih.gov/33118186

Probst V, Goronflot T, Anys S, Tixier R, Briand J, Berthome P, Geoffroy O, Clementy N, Mansourati J, Jesel L, Dupuis JM, Bru P, Kyndt F, Wargny M, Guyomarch B, Thollet A, Mabo P, Gourraud PA, Behar N, Sacher F, Gourraud JB. Robustness and relevance of predictive score in sudden cardiac death for patients with Brugada syndrome. Eur Heart J. 2021 May 1;42(17):1687-1695. doi: 10.1093/eurheartj/ehaa763.

Rahmi G, Coron E, Perrod G, Levy M, Moreau J, Moussata D, Perez-Cuadrado-Robles E, Chupin A, Quénéhervé L, Bourreille A, Marchal A, Cellier C, Peyrin-Biroulet L. Probe-based Confocal Laser Endomicroscopy for In Vivo Assessment of Histological Healing in Ulcerative Colitis: Development and Validation of the ENHANCE Index. J Crohns Colitis. 2021 Jun 22;15(6):994-999. doi: 10.1093/ecco-jcc/jjaa255.

Ronsin C, Georges M, Chapelet-Debout A, Augusto JF, Audard V, Lebourg L, Rubin S, Quemeneur T, Bataille P, Karras A, Daugas E, Titeca-Beauport D, Boffa JJ, Vigneau C, Halimi JM, Isnard-Bagnis C, Durault S, Renaudineau E, Bridoux F, Testa A, Le Quintrec M, Renaudin K, Fakhouri F. ANCA-Negative Pauci-Immune Necrotizing Glomerulonephritis: A Case Series and a New Clinical Classification. Am J Kidney Dis. 2021 Jun 11:S0272-6386(21)00637-5. doi:10.1053/j.ajkd.2021.03.027.

Sarafidis P, Ortiz A, Ferro CJ, Halimi JM, Kreutz R, Mallamaci F, Mancia G,Wanner C; ‘Hypertension and the Kidney’ working group of the European Society of Hypertension (ESH) and the ‘European Renal and Cardiovascular Medicine’ (EURECA-m) working group of the European Renal Association - European Dialysis and Transplant Association (ERA-EDTA). Sodium--glucose co-transporter-2 inhibitors for patients with diabetic and nondiabetic chronic kidney disease: a new era has already begun. J Hypertens. 2021 Jun 1;39(6):1090-1097. doi: 10.1097/HJH.0000000000002776. PMID: 33443971.

Semaan C, Charbonnier A, Pasco J, Darwiche W, Saint Etienne C, Bailleul X, Bourguignon T, Fauchier L, Angoulvant D, Ivanes F, Genet T. Risk Scores in ST-Segment Elevation Myocardial Infarction Patients with Refractory Cardiogenic Shock and Veno-Arterial Extracorporeal Membrane Oxygenation. J Clin Med. 2021 Mar 1;10(5):956. doi: 10.3390/jcm10050956.

Sevrain CM, Fontaine D, Bauduin A, Guéguinou M, Zhang BL, Chantôme A, Mahéo K, Pasqualin C, Maupoil V, Couthon H, Vandier C, Jaffrès PA. Thio-ether functionalized glycolipid amphiphilic compounds reveal a potent activator of SK3 channel with vasorelaxation effect. Org Biomol Chem (2021);19(12):2753-2766.

Ternant, D., Le Tilly, O., Picon, L., Moussata, D., Passot, C., Bejan-Angoulvant, T., Desvignes, C., Mulleman, D., Goupille, P., Paintaud, G.. 2021. Infliximab efficacy may be linked to full TNF-α blockade in peripheral compartment-A double central-peripheral target-mediated drug disposition (TMDD) Model. Pharmaceutics 13(11):1821. htpps://doi.org/10.3390/pharmaceutics13111821

Thoreau B, von Tokarski F, Bauvois A, Bayer G, Barbet C, Cloarec S, Mérieau, E, Lachot S, Garot D, Bernard L, Gyan E, Perrotin F, Pouplard C, Maillot F, Gatault P, Sautenet B, Rusch E, Frémeaux-Bacchi V, Vigneau C, Fakhouri F, Halimi JM. Infection in Patients with Suspected Thrombotic Microangiopathy Based on Clinical Presentation. Clin J Am Soc Nephrol. 2021 Sep;16(9):1355-1364.

Valensi P, Prévost G, Pinto S, Halimi JM, Donal E. The impact of diabetes on heart failure development: The cardio-renal-metabolic connection. Diabetes Res Clin Pract. 2021 May;175:108831. doi: 10.1016/j.diabres.2021.108831. Epub 2021 Apr 22. PMID: 33895192.